Disease: Acanthosis Nigricans
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
XRCC4 Q13426 X-ray repair cross complementing 4 8.3E-07 0.528 0.769
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
TGFA P01135 transforming growth factor alpha Signaling 0.72 0.432 0.885
SERPINF1 P36955 serpin family F member 1 Enzyme modulator 7.8E-08 0.460 0.846
SERPINE1 P05121 serpin family E member 1 Enzyme modulator 4.4E-02 0.359 0.885
RNF19A Q9NV58 ring finger protein 19A, RBR E3 ubiquitin protein ligase Enzyme 2.5E-02 0.397 0.923
PPARG P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 2.9E-02 0.358 0.885
POMC P01189 proopiomelanocortin 1.2E-04 0.356 0.846
POLDIP2 Q9Y2S7 DNA polymerase delta interacting protein 2 0.41 0.396 0.923
PNPLA2 Q96AD5 patatin like phospholipase domain containing 2 Enzyme 4.1E-03 0.511 0.846
PCNA P12004 proliferating cell nuclear antigen Nucleic acid binding 0.98 0.382 0.846
NTRK1 P04629 neurotrophic receptor tyrosine kinase 1 Kinase 2.0E-06 0.422 0.808
MAPK14 Q16539 mitogen-activated protein kinase 14 Kinase 0.37 0.379 0.923
MAPK1 P28482 mitogen-activated protein kinase 1 Kinase 1.00 0.330 0.923
LIPE Q05469 lipase E, hormone sensitive type 9.7E-12 0.599 0.500
LEP P41159 leptin 0.46 0.349 0.846
KRT18 P05783 keratin 18 0.73 0.530 0.692
KDR P35968 kinase insert domain receptor Kinase 1.00 0.378 0.885
INSR P06213 insulin receptor Kinase 3.6E-05 0.432 0.846
IL6 P05231 interleukin 6 0.32 0.248 0.962
IGF1R P08069 insulin like growth factor 1 receptor Kinase 0.97 0.399 0.885
HRAS P01112 HRas proto-oncogene, GTPase Enzyme modulator 8.0E-02 0.378 0.885
GRAP2 O75791 GRB2 related adaptor protein 2 1.5E-04 0.394 0.923
FOS P01100 Fos proto-oncogene, AP-1 transcription factor subunit Transcription factor 0.26 0.411 0.885
FGFR2 P21802 fibroblast growth factor receptor 2 Kinase 1.00 0.380 0.808